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Inheriting the Complications of Diabetes


Genetic susceptibility contributes to renal and cardiovascular complications of type 2 diabetes mellitus, by B.I. Freedman and colleagues. Hypertension 48:8-13, 2006


What is the problem and what is known about it so far?


Diabetes can lead to many complications, including cardiovascular disease (CVD, disease of the heart and blood vessels) and kidney disease. Some researchers have noticed that diabetes complications tend to run in families. But a clear genetic link between these diabetes complications has not been found.

Why did the researchers do this particular study?


The researchers wanted to see if there were any genetic qualities that make it more likely that a person would develop complications of diabetes, including cardiovascular and kidney disease.

Who was studied?


The researchers reviewed several papers that looked at genetic traits and diabetes complications.

How was the study done?


These studies looked at the genetic links to diabetes, its complications, and other diseases. The researchers put results from all the studies into one review.

What did the researchers find?


There are several studies that suggest links between specific genes and diabetes complications.

What were the limitations of the study?


The development of disease is often the result of genetic traits and the effects of diet and the environment. The presence of a genetic trait doesn't mean that a person will necessarily get diabetes. Like many diseases, diabetes involves numerous genes. There may be genes that affect the disease that researchers still don't know about.

What are the implications of the study?


Certain genes can increase the chances that a person with diabetes will develop cardiovascular or kidney disease. Identifying these genes may lead to better tests and treatments in the future.

FOR MORE INFORMATION


The Genetics of Diabetes

How to Prevent Pre-Diabetes

101 Tips for Staying Healthy



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